Spravato Treatment
Innovative Therapy for Treatment-Resistant Depression
At Heritage Health System, we are committed to providing advanced treatment options for individuals struggling with severe depression. One of the innovative therapies we offer is Spravato® (esketamine) treatment, an FDA-approved medication designed to help patients who have not responded adequately to traditional antidepressant medications.
What is Spravato®?
Spravato® (esketamine) is a prescription nasal spray medication approved by the U.S. Food and Drug Administration (FDA) for adults with:
• Treatment-Resistant Depression (TRD)
• Major Depressive Disorder (MDD) with suicidal thoughts or behaviors
Spravato is used in combination with an oral antidepressant and must be administered in a certified medical facility under professional supervision.


How Spravato Works?
Unlike traditional antidepressants that affect serotonin or norepinephrine, Spravato works on the NMDA receptor pathway in the brain, which helps regulate mood and emotional processing.
This mechanism may help:
• Restore neural connections in the brain
• Improve communication between brain cells
• Provide faster relief of depressive symptoms for some patients
Who May Benefit From Spravato Treatment?
Spravato may be recommended for patients who:
• Have not responded to two or more antidepressant medications
• Experience severe or persistent depression
• Need an alternative treatment approach for depression symptoms


What to Expect During Treatment?
Spravato is administered as a nasal spray in a certified treatment setting under the supervision of trained medical professionals.
Typical Treatment Process
Patient arrives at the clinic for the scheduled treatment session
The medication is administered under medical supervision
The patient remains in the clinic for approximately two hours of monitoring
Patients should arrange transportation home after the session
Contact Us for Medication Management.
Heritage Health System has dedicated its mission to offering superior medication management services in support of your mental health. We aim to enhance your treatment while guaranteeing you receive top-notch healthcare. Contact us now to arrange a meeting where you can discover how our complete medication management services can help enhance your well-being.


